Absolute Antibody Develops Custom Purification Systems to Enable High-Throughput Recombinant Antibody Production

By |2019-02-22T10:04:04+00:00February 22nd, 2019|Categories: Pivotal Scientific|

Absolute Antibody Develops Custom Purification Systems to Enable High-Throughput Recombinant Antibody Production New antibody purification robots support further company growth Oxford, UK, February 20, 2019. Absolute Antibody Ltd., an industry-leading manufacturer of recombinant antibodies, has developed custom protein purification systems to significantly increase its antibody production throughput. The automated robots, now installed in [...]

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Pivotal Links 2019 Agenda

By |2019-02-21T10:28:51+00:00February 21st, 2019|Categories: Pivotal Scientific|

Pivotal Links 2019 Agenda Tuesday 18th June 12.00                                     -             Registration Opens 12.00 – 17.00                     -              Pre-Organised One to One Meetings 18.30 – 19.30                     -              Aperitifs 19.30 – 22.00                     -              Networking Dinner Wednesday 19th June 8.30 – 9.00                          -             Registration Opens 9.00 – 9.45                          [...]

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Native Versus Recombinant Antigens – Which Is The Right Choice?

By |2019-02-19T15:21:10+00:00February 15th, 2019|Categories: Pivotal Scientific|

Native versus recombinant antigens – which is the right choice? A question we’re often asked is whether we can recommend an antigen provider. Of course, we can - with over a hundred members, the Pivotal Alliance includes many companies with a wealth of expertise in antigen generation. Yet for us to direct a client [...]

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Invasive Fungal Infections – Hidden Killers Requiring More Research

By |2019-01-24T09:55:07+00:00January 18th, 2019|Categories: Pivotal Scientific|

Invasive fungal infections  Hidden killers requiring more research When asked which field of scientific research they specialise in, many researchers will list a major discipline such as immunology or neuroscience; a disease area such as cancer or an inflammatory disorder; or a highly specialised field such as apoptosis or hypoxia. Yet while invasive fungal [...]

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Innovative Products Advancing Immunofluorescent Studies

By |2018-10-31T10:10:44+00:00October 31st, 2018|Categories: Pivotal Scientific|

Innovative Products Advancing Immunofluorescent Studies Offering the advantages of superior multiplexing, easier identification of co-localised molecules, and a dynamic range which affords visualisation of both high- and low-abundance targets within the same sample, it’s easy to see why researchers have employed immunofluorescent readouts for decades. Yet the need to detect an ever-growing number of [...]

New Tools to Monitor Cell Viability

By |2018-10-31T09:24:54+00:00October 17th, 2018|Categories: Pivotal Scientific, PSL Alliance, Scientific Techniques|

New Tools to Monitor Cell Viability Cell culture, the in vitro growth and maintenance of cells under carefully controlled conditions, is essential to scientific research. Used for applications which include evaluation of compound potency or cytotoxicity during drug development, large-scale manufacture of biologics, and comparison of cellular physiology under normal and diseased states, [...]

The Growing Need for Antibodies Targeting Fish Antigens

By |2018-09-20T12:27:25+00:00September 20th, 2018|Categories: Pivotal Scientific|

The Growing Need for Antibodies Targeting Fish Antigens While numerous antibodies have been developed against research targets of human, mouse and rat origin, significantly fewer are specific to fish antigens. Yet the importance of being able to detect fish antigens should not be under-estimated, especially with zebrafish increasingly being used as an alternative to rodents [...]

PROGEN’s Peptide Mapping Antibody Validation Initiative Earns CiteAb Commendation

By |2018-09-24T15:13:19+00:00June 28th, 2018|Categories: Pivotal Scientific|

PROGEN’s Peptide Mapping Antibody Validation Initiative Earns CiteAb Commendation   Scientists need reliable antibodies that generate reproducible data. German manufacturer PROGEN has launched a truly novel validation program that utilizes the peptide mapping technology of its collaborator PEPperPRINT to evaluate the performance of its antibodies. The peptide microarray platform enables the analysis of peptides covering [...]

Camelid Antibodies

By |2018-06-25T16:11:54+00:00June 25th, 2018|Categories: Pivotal Scientific|

Camelid Antibodies Immunoglobulins are widely used research tools, applicable to a huge diversity of laboratory techniques. Yet while we are all familiar with the five primary isotypes found in serum (IgG, IgA, IgM, IgE and IgD), the discovery that camelids (camels, llamas and alpacas) produce functional antibodies devoid of light chains has opened the [...]

Bispecific Antibodies

By |2018-06-15T12:18:53+00:00May 29th, 2018|Categories: Pivotal Scientific|

Bispecific Antibodies While a typical antibody molecule has two identical antigen-binding sites, bispecific antibodies (bsAbs) recognise two different epitopes. This makes them suitable for applications which include the recruitment of T cells to tumours, simultaneous blocking of two different signalling pathways, and the delivery of therapeutic agents to targeted sites. The most well-known bsAbs [...]

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