Innovative Products Advancing Immunofluorescent Studies

By |2018-10-31T10:10:44+00:00October 31st, 2018|Categories: Pivotal Scientific|

Innovative Products Advancing Immunofluorescent Studies Offering the advantages of superior multiplexing, easier identification of co-localised molecules, and a dynamic range which affords visualisation of both high- and low-abundance targets within the same sample, it’s easy to see why researchers have employed immunofluorescent readouts for decades. Yet the need to detect an ever-growing number of [...]

New Tools to Monitor Cell Viability

By |2018-10-31T09:24:54+00:00October 17th, 2018|Categories: Pivotal Scientific, PSL Alliance, Scientific Techniques|

New Tools to Monitor Cell Viability Cell culture, the in vitro growth and maintenance of cells under carefully controlled conditions, is essential to scientific research. Used for applications which include evaluation of compound potency or cytotoxicity during drug development, large-scale manufacture of biologics, and comparison of cellular physiology under normal and diseased states, [...]

The Growing Need for Antibodies Targeting Fish Antigens

By |2018-09-20T12:27:25+00:00September 20th, 2018|Categories: Pivotal Scientific|

The Growing Need for Antibodies Targeting Fish Antigens While numerous antibodies have been developed against research targets of human, mouse and rat origin, significantly fewer are specific to fish antigens. Yet the importance of being able to detect fish antigens should not be under-estimated, especially with zebrafish increasingly being used as an alternative to rodents [...]

PROGEN’s Peptide Mapping Antibody Validation Initiative Earns CiteAb Commendation

By |2018-09-24T15:13:19+00:00June 28th, 2018|Categories: Pivotal Scientific|

PROGEN’s Peptide Mapping Antibody Validation Initiative Earns CiteAb Commendation   Scientists need reliable antibodies that generate reproducible data. German manufacturer PROGEN has launched a truly novel validation program that utilizes the peptide mapping technology of its collaborator PEPperPRINT to evaluate the performance of its antibodies. The peptide microarray platform enables the analysis of peptides covering [...]

Camelid Antibodies

By |2018-06-25T16:11:54+00:00June 25th, 2018|Categories: Pivotal Scientific|

Camelid Antibodies Immunoglobulins are widely used research tools, applicable to a huge diversity of laboratory techniques. Yet while we are all familiar with the five primary isotypes found in serum (IgG, IgA, IgM, IgE and IgD), the discovery that camelids (camels, llamas and alpacas) produce functional antibodies devoid of light chains has opened the [...]

Bispecific Antibodies

By |2018-06-15T12:18:53+00:00May 29th, 2018|Categories: Pivotal Scientific|

Bispecific Antibodies While a typical antibody molecule has two identical antigen-binding sites, bispecific antibodies (bsAbs) recognise two different epitopes. This makes them suitable for applications which include the recruitment of T cells to tumours, simultaneous blocking of two different signalling pathways, and the delivery of therapeutic agents to targeted sites. The most well-known bsAbs [...]

Recombinant Antibodies in the Research Reagents Market…Implications and Opportunities

By |2018-06-15T12:18:53+00:00April 25th, 2018|Categories: Pivotal Scientific|

Recombinant Antibodies in the Research Reagents Market…Implications and Opportunities Antibodies continue to be big business. The global market for research reagents reached $2.8 billion in 2017 and the primary research antibodies global market is currently worth $945 million (Table 1). However, within the scientific community there have been growing concerns regarding the quality of [...]

Case Study – Mergers & Acquisitions

By |2018-06-15T12:18:53+00:00March 23rd, 2018|Categories: Industry Insights, Mergers & Acquisitions, Pivotal Scientific, PSL Alliance|Tags: |

Nordic-MUbio purchase of BioLogo One of the most critical steps in completing an Acquisition is to find a willing seller for an interested buyer.  Companies can spend so much time organizing themselves for sale yet never find a buyer where all the ‘stars align’. Nordic-MUbio (NM) has been well known over the past few [...]

Antibody Market Report 2018

By |2018-06-15T12:18:53+00:00March 23rd, 2018|Categories: Industry Insights, News, Pivotal Scientific|Tags: , |

Antibody Market Report 2018 At Pivotal Scientific this month, we are busy compiling our sixth annual Antibody Market Report. A yearly review of the international research antibody market, sharing industry knowledge and expertise in areas such as global research trends and online marketing. We are delighted to announce that this year’s report will include [...]

Organoid Research

By |2018-06-15T12:18:53+00:00February 19th, 2018|Categories: Industry Insights, Pivotal Scientific|Tags: , , |

Organoid Research It has long been known that cells cultured in two dimensions (2D) are not representative of the in vivo situation as a result of their growth being restricted to a flat surface. This minimises cell-cell and cell-matrix interactions, causing the distinctive phenotype to be lost and the cells to react differently to external [...]

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