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2023 In Review and Looking Forward To 2024

Pivotal Sci 4

As we say goodbye to the twelve days of Christmas and welcome a positive, upbeat-sounding JP Morgan conference in Boston, we know that an exciting new year has begun. It’s important when looking at a New Year to remember the challenges and achievements of the year just gone, analysing what went well and what was challenging, … Read more

Synthetic immune reagents as alternatives to antibodies raised in animals – Part 2

Antibody Engineering Recombinant Antibodies

Introduction The classic method to generate antibodies for research purposes is to immunize an animal with the protein of interest (or a part thereof), and allowing the animal to elicit an immune response to generate antibodies that specifically bind to the immunised protein. These antibodies can be purified from the serum or plasma. Standard protocols … Read more

Synthetic immune reagents as alternatives to antibodies raised in animals

Antibody Engineering Recombinant Antibodies

Introduction The classic method used to generate antibodies for research purposes is to immunize an animal with the protein of interest (or a part thereof), and allow the animal to elicit an immune response to generate antibodies that specifically bind to the immunised protein. The antibodies can then be purified from the serum or plasma. … Read more

Antibody Validation

Immunofluorescence

Time to get serious about antibody quality People in the research antibody business will be aware that discussions relating to the quality and validation of antibody quality have been rising over the last couple of years. General concerns relate to antibody specificity, sensitivity and batch to batch variation. When these factors are neglected, it could … Read more

3 reasons not to blame it on the Antibodies

Science 1

Introduction Antibodies have been pin pointed as the main culprit in the reproducibility issue surrounding the research reagents sector today. However is it too cynical and perhaps plain simplistic to place all the blame on the antibodies alone? Could it be that it is not just the antibodies that are the issue, but the way … Read more