How CRISPR is Helping in The Battle Against Cancer


CRISPR Introduction CRISPR-Cas9 gene editing, found in nature as a bacterial immune defence mechanism, was first harnessed by scientists as a laboratory tool in 2012 to knock out or mutate genes of interest.(1,2,3) This ground-breaking technique is now commonly used on cell lines to monitor the effects of specific mutations or the function of a specific … Read more

Plastic, Pollution and A New Bacterial Hope for Recycling


Introduction There have been growing concerns over the amount of plastic waste being released into the environment, especially into our oceans. This is because of the untold harm to aquatic life and contamination of the food chain. In fact, plastics can enter the food chain through tiny plastic particles, known as microplastics, that can be … Read more

Introduction to Phage Display


What are Phages? A phage (an abbreviated term for a bacteriophage) is a virus that infects bacteria. They are made up of of a nucleic acid molecule that is surrounded by a protein structure. Phages produce viral components by first hijacking the cellular machinery of a bacterium. These viral components are then assembled to form … Read more

Bio-Helix Exclusive B2B Free Trial Offer!

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PSL Alliance Member Bio-Helix has been in the life sciences research market for 12 years providing top quality, ISO 9001:2008 certified, molecular biology reagents to researchers globally. Bio-Helix brands GeneDirex, PureDirex and now LifeDirex offer a product range that includes DNA markers, protein ladders, nucleic acid purification kits, western blotting solutions, enhanced chemiluminescent (ECL) substrates … Read more

Mergers & Acquisition (M&A) – The Pivotal Scientific Way

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M&A In the Research Reagents Market The market in research reagents and diagnostics has been very active in the latter part of 2018 and early 2019 with a large number of M&A transactions undertaken. Most of these appear to have been by private equity expanding their platform approach either in specific product groups or across … Read more

Antibodies… What Are The Alternatives?

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The use of antibodies in research is well established with an estimated research reagent market size of $1.4 billion. Furthermore, the value of the therapeutic antibody market is considerably larger, with antibody-based drugs in clinical use to treat conditions such as cancer, rheumatoid arthritis and Crohn’s disease. In addition, the recent growth of the antibody … Read more

Pivotal Links Testimonial – Vertebrate Antibodies

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“Vertebrate Antibodies was established in 2011 by four scientists; including myself, Abdo, Steve and Beatriz. In the beginning, we had a very academic focus through collaborations with prominent scientists such as Professors Graeme Murray and Christopher Secombers, promoting and citing Vertebrate Antibodies’ products through international conferences and publications. Jump forward to 2017 and although product … Read more

Antibody Validation… Is There Still A Crisis?

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Reliable antibodies are essential for reproducibility. Likewise, reproducibility is key whether you are planning to publish a ground-breaking research, or are carrying out routine assays. Therefore, reliable antibodies is a topic that is is frequently visited and discussed by the scientific community. Initially, there was a greater onus on the researcher to check an antibody … Read more

Absolute Antibody Launches Mouse Bispecific Antibody Reagents

Antibody Engineering Recombinant Antibodies

Novel fully murine knob-into-hole antibodies for immunotherapy research and drug development Oxford, UK, May 7, 2019. Absolute Antibody Ltd., an industry-leading provider of recombinant antibodies products and services, today announced the launch of the first commercially available mouse knob-into-hole (KIH) bispecific antibody reagents. Bispecific antibodies, which permit simultaneous engagement of two different protein targets, are an … Read more